9A3Q | pdb_00009a3q

Modeling hLINE1 ORF2p

Integrative structure models are generated using different types of input information, including varied experimental data, physical principles, statistical preferences, and other prior information.

PDB DOI: https://doi.org/10.2210/pdb9A3Q/pdb

Organism(s): Homo sapiens
Mutation(s): No

Deposited: 2023-05-25 Released: 2024-01-05
Deposition Author(s): Baldwin, E.T., van Eeuwen, T., Hoyos, T., Zalevsky, A., Tchesnokov, E.P, Sanchez, R., DiStefano, L., Ruiz, F.X, Hancock, M., Walpole, T., Nichols, C., Wan, P., Riento, K., Kass, R.-H., Augustin, M., Lammens, A., Jestel, A., Upla, P., Xibinaku, K., Congreve, S., Hennink, M,, Rogala, K.B., Schneider, A.M., Fairman, J.E., Christensen, S.M., Miao, W., Zaller, D.M., Sali, A., Weichenrieder, O., Burns, K.H., Gotte, M., Rout, M.P., Arnold, E., Greenbaum, B.D., Romero, D.L., LaCava, J., Taylor, M.S.

Integrative Structure Snapshot

Multi-Scale: Yes
Multi-State: No
Ordered-State: No
Deposited Models: 159
Representative Model: 1

wwPDB ValidationFull ReportSummary Report

This is version 1.0 of the entry. See complete history.

Literature

Structures, Functions, and Adaptations of the Human LINE-1 ORF2 Protein

Baldwin, E.T., van Eeuwen, T., Hoyos, T., Zalevsky, A., Tchesnokov, E.P, Sanchez, R., DiStefano, L., Ruiz, F.X, Hancock, M., Walpole, T., Nichols, C., Wan, P., Riento, K., Kass, R.-H., Augustin, M., Lammens, A., Jestel, A., Upla, P., Xibinaku, K., Congreve, S., Hennink, M,, Rogala, K.B., Schneider, A.M., Fairman, J.E., Christensen, S.M., Miao, W., Zaller, D.M., Sali, A., Weichenrieder, O., Burns, K.H., Gotte, M., Rout, M.P., Arnold, E., Greenbaum, B.D., Romero, D.L., LaCava, J., Taylor, M.S.

(2023) Nature

DOI: https://doi.org/10.1038/s41586-023-06947-z

Macromolecule Content

Total Structure Weight: 172.21 kDa
Modeled Residue Count: 1,275
Deposited Residue Count: 1,275
Unique protein chains: 1

Macromolecules

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| 3D Structure

Entity ID: 1
Molecule	Chains	Sequence Length	Organism	Details	Image
ORF2	A	1,275	Homo sapiens	Mutation(s): 0 EC: 2.7.7.49 (UniProt), 3.1.21 (UniProt)
UniProt
Find proteins for O00370 (Homo sapiens) Explore O00370 Go to UniProtKB: O00370
Entity Groups
Sequence Clusters	30% Identity 50% Identity 70% Identity 90% Identity 95% Identity 100% Identity
UniProt Group	O00370
Sequence Annotations Expand
Reference Sequence